John J. Warner, MD, CEO of The Ohio State University Wexner Medical Center and Executive Vice President at Ohio State | Ohio State University Wexner Medical Center
+ Pharmaceuticals
Patient Daily | Dec 24, 2025

How households can prepare emergency over-the-counter medicine kits safely

When preparing for emergencies, selecting and storing over-the-counter (OTC) medicines can be important for households looking to manage unexpected health issues. Pain relievers such as ibuprofen, naproxen, and acetaminophen are often recommended for managing aches or fever. However, certain conditions may limit their use; people with stomach ulcers or poor kidney function should avoid ibuprofen and naproxen, while acetaminophen should not be used in combination with alcohol.

Aspirin, particularly chewable or non-coated forms, can play a role in emergency situations involving chest pain but should only be taken when directed by emergency medical services personnel due to its antiplatelet effects.

For allergy management, diphenhydramine is suitable for severe allergic reactions but may cause drowsiness. Alternatives like cetirizine or loratadine are preferred for everyday allergies because they are less likely to induce sleepiness.

Antacids such as calcium carbonate provide quick relief from heartburn and offer an additional source of calcium. For minor injuries, having bandages in various sizes and ointments on hand is advised. While antibiotic ointment can help protect wounds, thorough washing with soap and water is often sufficient.

Households may also consider expanding their medicine supplies to address constipation—with options like stimulant laxatives (senna, bisacodyl) or stool softeners—and coughs or colds using cough drops and other remedies tailored to specific symptoms. Supplements such as melatonin or magnesium glycinate might assist with sleep issues during stressful times.

Other recommended items include creams and ointments for skin care, thermometers for temperature checks, blood pressure cuffs and blood sugar tests for those managing chronic conditions like diabetes or hypertension, and glucose tablets for hypoglycemia.

It is important to regularly check the expiration dates of OTC medications since most remain effective for about a year. Expiration dates reflect the period during which at least 90% of the active ingredients remain effective; however, there is limited research on how medications degrade after this point. Building up a supply can be done gradually based on household needs and budget constraints. Some OTC items are available in smaller quantities at discount stores, making it easier to purchase essentials over time. Additionally, individuals enrolled in flexible savings accounts (FSAs) or health savings accounts (HSAs) may use these funds to reimburse eligible OTC purchases if available.

Medication storage plays a critical role in maintaining effectiveness. Medicines should be kept in areas with stable temperatures and low humidity—ideally out of reach of children and pets. Suitable locations include kitchen cabinets away from heat sources or nightstands with secure drawers. Bathrooms are generally discouraged due to fluctuating humidity levels that could affect medication quality.

Annual reviews of medicine cabinets—potentially timed with daylight saving changes—can help ensure expired products are discarded appropriately. Participation in community drug takeback days provides another safe disposal option.

Certain health conditions may make some OTC medicines unsafe; patients are encouraged to consult healthcare providers about individual risks related to liver or kidney function before using common pain relievers like acetaminophen or ibuprofen. Checking drug labels helps prevent accidental duplication of active ingredients across multiple products.

"Choosing which over-the-counter medicines to keep at home depends on your health, what you have easy access to and what you can afford."

"If you’re preparing for the unexpected, you can expand to add the following medications..."

"It’s also good to keep any go-to items on hand that work well for you."

"When taking a product, be sure to look at the drug facts label."

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