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Patient Daily | Apr 16, 2026

Study links treatable ear conditions to higher dementia risk, finds treatment may lower odds

A study published in Otolaryngology–Head and Neck Surgery, the official journal of the American Academy of Otolaryngology–Head and Neck Surgery Foundation, reports on Apr. 13 that eardrum perforations and cholesteatoma are linked to higher odds of developing dementia. The research also finds that treating these conditions through surgery or hearing aids is associated with a reduction in this elevated risk.

The findings are significant as they add to evidence connecting hearing loss with cognitive decline. The study raises questions about whether addressing the underlying causes of hearing loss could help protect brain health.

Researchers from Columbia University and the University of Utah analyzed data from over 363,000 participants enrolled in the All of Us Research Program, a national health dataset sponsored by the National Institutes of Health. According to their analysis, individuals with eardrum perforations had more than double the odds of developing dementia compared to those without such conditions. Those diagnosed with cholesteatoma faced nearly twice the odds. In contrast, otosclerosis—a condition affecting bones in the middle ear—did not show a significant link to dementia.

The study found that when surgical treatment was considered for cholesteatoma patients, its association with dementia was no longer significant. Similarly, using hearing aids reduced the connection between both ear conditions and dementia risk. This suggests that restoring hearing may play an important role in lowering chances for cognitive decline.

These results highlight potential benefits from early detection and treatment of certain types of conductive hearing loss for long-term brain health.

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