Ian Birkby, CEO at News-Medical | News-Medical
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Patient Daily | Jan 23, 2026

Researchers create 3D-printed microscopic structures inside living cells

Researchers have introduced a technique to 3D print micrometer-sized structures inside living cells. The method, described in Advanced Materials, allows for the creation of complex microstructures such as barcodes, geometric patterns, and even a miniature elephant within the cellular environment.

The process works by injecting a bio-compatible light-sensitive material, known as photoresist, into the cell. A specialized laser is then used to polymerize the photoresist, forming an intracellular structure with submicron precision. According to the researchers, "A cell treated with this method not only contains the newly fabricated structure within its interior, but also keeps on living and dividing, passing the structure on to one of the daughter cells that result from cell division."

While still in early stages, this technology may enable scientists to print small devices or machines inside cells. Such advancements could lead to better understanding of biological processes or give cells new or enhanced properties.

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