The Global Virus Network (GVN), an international group of virologists, has issued a statement regarding the recent confirmation of Marburg virus disease (MVD) in southern Ethiopia. This marks the first time Marburg virus has been documented in the country and highlights urgent needs for public health response, research, and surveillance.
The World Health Organization (WHO) confirmed the outbreak on November 14, 2025. Initial suspected cases of viral hemorrhagic fever were identified in Jinka town, South Omo Region, Ethiopia. Testing revealed the presence of Marburg virus RNA. As of November 20, six laboratory-confirmed cases have been reported, including three deaths. There are also three probable deaths under investigation that are epidemiologically linked to the outbreak. Authorities are monitoring 206 contacts, with that number expected to increase.
Prof. Kaleebu highlighted several immediate research and management priorities: "This outbreak also presents an opportunity to advance much-needed vaccine and therapeutic research for Marburg virus," Prof. Kaleebu said. "Scientific studies involving survivors, including immunologic responses and viral shedding over time, will be essential to strengthen global preparedness."
The GVN noted that the outbreak’s proximity to borders with South Sudan and Kenya could lead to cross-border transmission. The Africa Centers for Disease Control and Prevention (Africa CDC) is providing support to Ethiopia through diagnostics, genomic sequencing capabilities, and bio-surveillance.
Professor Salim S. Abdool Karim, director of CAPRISA—a GVN Center of Excellence—and chair of Africa CDC's Emergency Consultative Group on continental public health emergencies commented: "The detection of Marburg virus in Ethiopia for the first time is a stark reminder of how quickly viral threats can emerge in new regions. It reinforces the need for strong surveillance systems, rapid diagnostic capacity, and scientific partnerships across Africa." He added: "Africa has the scientific leadership, laboratory capabilities, and field experience to confront outbreaks like this, but investment in preparedness must be sustained not just during crises."
GVN stated it will continue working with partners across Africa and internationally to monitor developments and support response efforts as well as long-term strategies against future Marburg virus threats.
