FluMist, a nasal flu vaccine spray, received approval from the U.S. Food and Drug Administration in September for at-home use starting in fall 2025. Presently, it is only administered by healthcare providers. Dr. Pedro Piedra of Baylor College of Medicine explains FluMist's characteristics, effectiveness, and suitability for individuals.
FluMist is a live attenuated influenza vaccine designed to be sprayed into the nose rather than injected. It contains a weakened flu virus targeting three strains and is approved for children aged two years and older up to adults aged 49.
"Instead of an injection, there is a live vaccine administered by spray into the nose to give a good immune response so that the nose and respiratory system is better prepared against influenza," Piedra stated.
The nasal spray suits healthy children and adults, particularly those who prefer not to receive injections. "The immune response is good for both children and adults," said Piedra. However, he noted that some might experience mild reactions such as a cold or sore throat due to the live virus replicating in the nasal passage.
Regarding its effectiveness, FluMist has shown comparable levels to traditional inactivated vaccines within its intended age range but isn't recommended for immunodeficient or immunocompromised individuals. The nasal spray may cause wheezing in children under five with recurrent wheezing histories.
"Also, older children and adults with significant lung disease should speak with their physician to see if there is an alternative vaccine that will not predispose them to a potential wheezing episode," advised Piedra.
Before using FluMist, avoid antiviral medications for two weeks since they can interfere with the vaccine's efficacy by halting viral replication needed for an immune response. Children should also refrain from taking aspirin products due to Reye’s syndrome risks associated with live vaccines like FluMist.
For those considering at-home administration next fall, it offers flexibility regarding timing without disrupting daily routines significantly. "You can dictate the timing of the vaccine without truly affecting much of your routine," said Piedra.
However, caution is advised when using FluMist around immunodeficient individuals; consulting with physicians about suitable vaccination options remains crucial for family protection against influenza.
